Cortical relay time shortens in parkinson’s disease with apraxia Parkinson hastalığiı'da kortikal röle zamani kisalir


Gunduz A., Kiziltan M. E. , Kumru H., OĞUZ S., Kiziltan G., Ertan S., ...More

Journal of Neurological Sciences, vol.34, no.3, pp.215-221, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.24165/jns.9736.16
  • Journal Name: Journal of Neurological Sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.215-221
  • Istanbul University-Cerrahpasa Affiliated: Yes

Abstract

© 2017, Ege University Press. All rights reserved.Cortical relay time (CRT) is a neurophysiologic method that measures transmission between sensory and motor cortices. In this study, we calculated CRT to evaluate intrahemispheric transmission in idiopathic Parkinson’s disease (PD). We recorded the following parameters: 1) long latency reflexes (LLRs), 2) motor-evoked potentials (MEPs), and 3) somatosensory- evoked potentials (SEPs) according to previously published reports, and cortical relay time was calculated using the following formula: Latency of LLR II - (onset latency of MEP response + latency of N20 response of SEP). CRT was shorter in patients with apraxia compared with patients without apraxia. The findings may raise the possibility of intrahemispheric aberrant conduction or abnormal synaptic reorganization in the presence of apraxia in PD.