Crucial Roles of Systemic and Tissue Lipid Peroxidation Levels and Anti-Oxidant Defences Following Contrast Agent Application

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SITAR G., KUCUK M., Sitar M. E., Yasar O., Aydin S., Yanar K., ...More

IRANIAN RED CRESCENT MEDICAL JOURNAL, vol.18, no.6, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.5812/ircmj.37331
  • Journal Name: IRANIAN RED CRESCENT MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Contrast Media, Lipid Peroxidation, Nephropathy, Oxidative Stress, Oxidation Protein, OXIDATION PROTEIN PRODUCTS, INDUCED NEPHROPATHY, ACETYLCYSTEINE, DISEASES, RISK, RATS
  • Open Archive Collection: AVESIS Open Access Collection
  • Istanbul University-Cerrahpasa Affiliated: No

Abstract

Background: One of the most important side effects of contrast pharmaceutical agents, which are used very common in routine radiology practice, is contrast induced nephropathy. Even ischemia, oxidative stress and osmolality related cytotoxic effects are considered, the molecular mechanisms underlying this pathology have not been identified completely yet.