Turkiye Klinikleri Jinekoloji Obstetrik, cilt.24, sa.3, ss.147-152, 2014 (Scopus)
Copyright © 2014 by Türkiye Klinikleri.Objective: Objective evaluation of sulcal development of fetuses without abnormalities with transabdominal ultrasound and present normograms correlated to the gestational age. Material and Methods: 332 pregnant women refering to Istanbul University Cerrahpasa Medical Faculty, Department of Obstetrics and Gynecology for routine antenatal follow-up between November 2011-October 2012 were examined for anatomical early visibility and size of the parieto-occipital sulcus, calcarine sulcus and the cingulate sulcus and the correlation of the values with the gestational age. Gestational age of fetuses included in the study were between 15 and 31 weeks. Parieto-occipital sulcus length was obtained in axial plan by measuring echogenic area at the level of lateral ventricle up to the falx cerebri, calcarin sulcus length was obtained in coronal plan where cerebellum can be seen as echogenic area just above tentorium, cingulate sulcus length was obtained in midcoronal plan measuring echogenic line up to the falx cerebri. Results: We were able to measure parieto-occipital sulcus and calcarine sulcus earliest at 17th weeks of gestation. The cingulate sulcus that we detected in the earliest gestational week was 25. We found out that parieto-occipital sulcus, calcarine sulcus and cingulate sulcus all can be seen at 27 gestational weeks. We obtained positive correlation between gestational age and parietooccipital sulcus, calcarine sulcus and the cingulate sulcus length values (respectively r=0.825, p<0.001, r=0.786, p<0.001, r=0.450, p<0.001), respectively. Conclusion: It is possible to evaluate sulcal development and cortical maturation through examining CNS with prenatal ultrasound. Knowing development of each sulcus according to the gestational age in intrauterin sulcal development may allow the early detection of abnormalities of cortical development.