Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon, cilt.30, sa.1, ss.17-21, 2002 (Scopus)
Analgesic efficacy and side effects of two different doses of bupivacaine combination with morphine were evaluated in 96 children undergoing lower abdominal and major urologic operations. Following intubation, patients were randomly allocated into two groups. In Group I (n=56) 0.05 mg/kg morphine in 0.25% bupivacaine 1 mL/kg and in Group II (n=40) 0.05 mg/kg morphine in 0.166% bupivacaine 1 mL/kg were given lumbar epidurally. During peroperative period, systolic arterial pressure (SAP) and heart rate (HR) were recorded. Motor block was evaluated. SAP, HR, respiratory rate, pain score, sedation level and side effects were recorded every 2 hours throughout 24 hours. There were significantly decreases in SAP and HR in both groups after epidural block compared with control values (p<0.001). In Group I, HR and SBP clinically decreased in 9 and 8, in 2 and 1 patients for Group II, respectively. However, There was no statistically difference (p>0.05). Motor block was not seen in any patient. In Group I and II, 76.7% and 87.5% of patients did not require analgesic, respectively (p>0.05). There were no differences in pain and sedation scores between the groups. The incidences of nausea-vomiting and pruritis were 39.2%-40% and 8.9%-10% in Group I and II, respectively (p>0.05). Cardi-ovascular and respiratory complication were not seen. We suggesse to use 1 mL/kg 0.166% bupivacaine combination with morphine in children since there is no difference regarding analgesic efficacy between two bupivacaine doses.