The positive immunostaining of TMPRSS2-ERG is not associated with unfavourable outcomes and biochemical recurrence after radical prostatectomy in Turkish patients

Gumrukcu G., Celik B. O., Caliskan S., Okzara S., Koca O., Tosun C., ...Daha Fazla

CENTRAL EUROPEAN JOURNAL OF UROLOGY, cilt.71, sa.3, ss.276-279, 2018 (ESCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 71 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5173/ceju.2018.1708
  • Dergi Adı: CENTRAL EUROPEAN JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.276-279
  • Anahtar Kelimeler: biochemical recurrence, prostate cancer, TMPRSS2:ERG fusion, GENE FUSION, CANCER, ERG, COHORT, REARRANGEMENT
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Introduction Prostate cancer is the second most common cancer and a major significant health problem amongst men in the world. Radical prostatectomy with open, laparoscopic and robotic techniques is the gold standard treatment for localized and local advanced disease. There are some risk factors including gleason score, T stage and prostate-specific antigen (PSA) level to predict the biochemical recurrence. We investigated the association with biochemical recurrence and TMPRSS2:ERG fusion in patients who were treated with open radical prostatectomy.