Research on Microwave-Assisted Synthesized Cu²+- and Zn²+-Doped β-TCP Powders

22. Uluslararası Metalurji ve Malzeme Kongresi (IMMC 2024), İstanbul, Türkiye, 19 - 21 Eylül 2024, ss.672, (Özet Bildiri)

β-tri-calcium phosphate (β-TCP) is a famous calcium-phosphate-based bioceramic material with a 1.5 (Ca/P) molar ratio. As a

bioresorbable ceramic, it promotes bone regeneration. Therefore, β-TCP is commonly used in orthopedic implant applications

for bone repair. There are several methods to prepare β-TCP powders, however, the microwave-assisted synthesis technique

draws attention due to its advantages such as being more rapid, practical, cost-effective, and environmentally friendly. Since

heating starts and proceeds from the inner structure of the material, which is the mixture of the Ca and P solutions in this case,

the synthesis reaction occurs pretty fast. Furthermore, various ions can be introduced to the β-TCP lattice to enable the material

to gain different features such as being antibacterial. For instance, Cu²⁺ ions are known to provide antibacterial properties, while

Zn²⁺ ions have positive effects on the development/growth of bone tissue. In this study, Cu2+ and Zn2+ doped β-TCP particles

were obtained via the microwave-assisted synthesis method. It was aimed to manage the ion-incorporated powders with less

agglomeration and uniform, sub-micron-sized particles. As conventional wet chemical synthesis processes involve many

parameters and experimental steps, it becomes challenging to provide and sustain the control of these factors. On the contrary,

the microwave-assisted synthesis technique appears as a time-saving and feasible remedy. After sequentially applying the steps,

i.e. preparation of the Ca and P source solutions, the reaction between them, centrifuging & washing, drying, and heat treatment,

finally the ion-doped β-TCP powders were achieved. X-Ray Diffraction (XRD), Fourier-Transform Infrared Spectroscopy (FTIR),

and Scanning Electron Microscope (SEM) analyses were performed to examine the chemical phase, molecular bonding,

and microstructure properties of the generated β-TCP powders, respectively.