COX-2 GENE VARIANTS IN BIPOLAR DISORDER-I

ÖZDEMİRCAN A. , DAŞDEMİR S., KÜÇÜKALİ C. İ. , Bireller E. S. , Ozturk H., ÇAKMAKOĞLU B.

PSYCHIATRIA DANUBINA, vol.27, no.4, pp.385-389, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2015
  • Title of Journal : PSYCHIATRIA DANUBINA
  • Page Numbers: pp.385-389

Abstract

Background: Bipolar disorder-I (BD-I) is a complex illness, and multiple genes and environmental factors determine its pathogenesis. Several studies have ascertained that BD-I and inflammation are linked through shared genetic polymorphisms and gene expression, as well as altered cytokine levels. COX-2 gene polymorphisms affecting COX-2 levels may be associated with BD-I by altering the inflammatory response.