The comparison of decision-making in ambiguous situations and galvanic skin responses as somatic markers in patients with posterior cortex epilepsy and mesial temporal lobe epilepsy with hippocampal sclerosis

Şandor S., Yağcı Kurdish S., Delil Ş., Türk B. G., Yeni S. N.

JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, sa.10, ss.743-754, 2022 (SCI-Expanded, SSCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/13803395.2022.2164256
  • Dergi Adı: JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, PASCAL, AgeLine, Educational research abstracts (ERA), EMBASE, Linguistics & Language Behavior Abstracts, MEDLINE, Psycinfo
  • Sayfa Sayıları: ss.743-754
  • Anahtar Kelimeler: Posterior cortex epilepsy, decision-making, somatic marker hypothesis, mesial temporal lobe epilepsy, neuropsychological tests, VENTROMEDIAL PREFRONTAL CORTEX, HYPOTHESIS, AMYGDALA, RISK, IMPULSIVITY, ADDICTION, PARIETAL, SURGERY, MEMORY
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

IntroductionDecision-making behaviors of patients with mesial temporal lobe epilepsy (MTLE) is a subject that has been studied frequently. However, determining the neuropsychological profiles of patients with different types of epilepsy is also important. Our main purpose was to examine the decision-making behaviors of patients with posterior cortex epilepsy (PCE) through the assumptions of somatic marker hypothesis (SMH) and to compare their performances with those of a MTLE group and a control group.MethodParticipants comprised of 13 patients with PCE (mean age 30.92 +/- 9.99 years); 14 patients with MTLE with hippocampal sclerosis (MTLE-HS) (mean age 25.53 +/- 7.40 years) and 15 controls (mean age 24.60 +/- 8.45 years). Decision-making performances were assessed with the Iowa gambling test (IGT) and anticipatory skin responses before each choice were recorded. A comprehensive neuropsychological test battery was also given to all participants in order to examine the relationship of decision-making with other cognitive functions.ResultsAnticipatory responses before choosing from disadvantageous decks were significantly larger than choosing from advantageous decks in the PCE group (p = 0.00). No significant difference was found between the PCE and control group's total net scores. IGT total net scores was significantly correlated with Stroop test interference time (p = 0.03).ConclusionThe study reveals that cognitive impairments of patients with PCE are not limited to brain's posterior areas' functions, and provides evidence for the current paradigm which understands epilepsy as a network disorder.