An association analysis at 2q36 reveals a new candidate susceptibility gene for juvenile absence epilepsy and/or absence seizures associated with generalized tonic-clonic seizures

Yalcin, Ozlem; Baykan, Betul; AĞAN YILDIRIM, KADRİYE; Yapici, Zuhal; Yalcin, Destina; Dizdarer, Gulsen; TÜRKDOĞAN, DİLŞAD; Ozkara, ÇİĞDEM; Unalp, Aycan; Uluduz, Derya; Gul, Gunay; Kuscu, Demet; Ayta, Semih; Tutkavul, Kemal; Comu, Sinan; Tatli, Burak; Meral, Cihan; Bebek, Nerses; ÇAĞLAYAN, Server

doi:10.1111/j.1528-1167.2010.02970.x

An association analysis at 2q36 reveals a new candidate susceptibility gene for juvenile absence epilepsy and/or absence seizures associated with generalized tonic-clonic seizures

Yalcin O., Baykan B., AĞAN YILDIRIM K., Yapici Z., Yalcin D., Dizdarer G., ...Daha Fazla

EPILEPSIA, cilt.52, sa.5, ss.975-983, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 52 Sayı: 5
Basım Tarihi: 2011
Doi Numarası: 10.1111/j.1528-1167.2010.02970.x
Dergi Adı: EPILEPSIA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.975-983
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Purpose: To further evaluate the previously shown linkage of absence epilepsy (AE) to 2q36, both in human and WAG/Rij absence rat models, a 160-kb region at 2q36 containing eight genes with expressions in the brain was targeted in a case-control association study involving 205 Turkish patients with AE and 219 controls.