Akademik Veri Yönetim Sistemi
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, cilt.92, 2025 (SCI-Expanded, Scopus)
In this study, the extraction and characterization of bioactive compounds from Spirulina platensis were investigated after the cultivation of the biomass. Automated solvent extraction (ASE) was carried out under the optimized conditions (68.14 % ethanol, 1 g sample, and 30 min immersion time) determined through a Box-Behnken Design (BBD). Gas Chromatography-Mass Spectrometry (GC-MS) analysis identified the predominant volatile compounds (VOCs) as hexadecanoic acid, 2(4H)-Benzofuranone and phytol. The extract rich in these main VOCs showed significant antioxidant activities as determined by DPPH (2, 2 '-azinobis (3-ethylbenzothiazoline-6-sul-phonic acid)) and FRAP (ferric ion reducing antioxidant power) assays. The antioxidant activity (IC50) value was of 90.15 mu g/mL based on the DPPH assay, while a reducing power of 438 mu mol Fe2+/g extract was calculated according to the FRAP assay. Additionally, influential inhibitory activity against various pathogenic bacteria and fungi (particularly Staphylococcus aureus and Candida albicans) was observed depending on the antimicrobial tests (disk diffusion and microdilution methods).