Depression associated with valsartan, angiotensin II receptor antagonist; case report and review of the literature Anjiyotensin II reseptör antagonisti valsartan ile ilişkili depresyon; olgu bildirimi ve literatürün gözden geçirilmesi

Konuk N., Aydin M., Akay Ö.

Klinik Psikofarmakoloji Bulteni, cilt.15, sa.4, ss.187-191, 2005 (Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 15 Sayı: 4
  • Basım Tarihi: 2005
  • Dergi Adı: Klinik Psikofarmakoloji Bulteni
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.187-191
  • Anahtar Kelimeler: Angiotensin receptor antagonists, Drug induced depression, Valsartan
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Severe depression with suicidal ideation associated with the use of the valsartan, an angiotensin receptor antagonist, is reported. The patient, who was unresponsive to antidepressant medication with two different groups, dramatically recovered following discontinuation of valsartan. Possible mechanisms and related issues of mood changes which caused by angiotensin II receptor antagonists, especially with valsartan are discussed. Clinicians should be aware that valsartan may cause mood changes.