Postpartum Budd-Chiari syndrome in a woman with primary thrombocythemia

Mungen E., Madazli R. , Ertekin A., Yergok Y., Sen C.

Journal of Maternal-Fetal Investigation, vol.6, no.4, pp.228-230, 1996 (Journal Indexed in SCI Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 4
  • Publication Date: 1996
  • Title of Journal : Journal of Maternal-Fetal Investigation
  • Page Numbers: pp.228-230


Objective: To report the first case of postpartum Budd-Chiari syndrome in a patient with primary thrombocythemia, and to emphasize that serious maternal and fetal complications may occur during pregnancy and postpartum period in patients with primary thrombocythemia. Methods: A pregnant woman with primary thrombocythemia diagnosed during pregnancy was treated with platelet-pheresis and aspirin (80 mg/day) during pregnancy. The course of pregnancy and complications occurring during pregnancy and postpartum period were evaluated. Results: The patient developed oligohydramnios and fetal growth retardation at 32 weeks' gestation. A viable female infant was delivered by cesarean section at 34 weeks' gestation. Hepatic vein thrombosis occurred 3 weeks after cesarean section. The various treatment schedules had no beneficial effect on the course of disease and the patient died 5 months after the diagnosis of hepatic vein thrombosis. Conclusion: Patients with primary thrombocythemia should be followed closely for maternal and fetal complications during pregnancy and postpartum period.