Presence of antibodies to Rift Valley fever virus in children, cattle and sheep in Turkey


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Yılmaz A., Yılmaz H., Faburay B., Karakullukçu A., Barut K., Çizmecigil U. Y., ...Daha Fazla

10th International Congress on Clinical Virology, Fungal Infections, Infectious Disease, Dubai, Birleşik Arap Emirlikleri, 4 - 05 Aralık 2017, cilt.6, sa.4, ss.29, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 6
  • Doi Numarası: 10.4172/2324-8955-c1-003
  • Basıldığı Şehir: Dubai
  • Basıldığı Ülke: Birleşik Arap Emirlikleri
  • Sayfa Sayıları: ss.29
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Rift Valley fever virus is a zoonotic pathogen that causes severe disease in humans and livestock. The virus has great potential for transboundary spread given the presence of competent vectors in traditionally non-endemic areas. Given the historic outbreak of RVFV in neighboring Saudi Arabia and Yemen in the Middle Rast, we investigated the potential risk of RVFV infection in Turkey. Using indirect IgG ELISA, western blot and quantitative RT-PCR, we tested sera obtained from a cohort of children (n=110) with fever and/or arthritis, cattle (n=200) and sheep (n=160) to assess potential exposure to RVFV. While results of RT-PCR assay were negative, antibodies to RVFV were detected in all three study populations: human (3.64%), cattle (4.5%) and sheep (3.75%). These results suggest the occurrence of low level circulation and transmission of RVFV in humans and livestock in Turkey during interepidemic periods; and we therefore recommend further comprehensive and systematic studies to elucidate the true prevalence, risk and impact of RVFV infection in the country.