Research Information System
CUKUROVA MEDICAL JOURNAL, vol.39, no.3, pp.641-645, 2014 (ESCI, TRDizin)
Acute necrotizing encephalopathy of childhood is a rare form of acute encephalopathy of unknown etiology characterized by typical symmetrical lesions in the thalami, with variable involvement of the white matter, brainstem and cerebellum. Clinically there is a rapid neurologic deterioration after a short period of a nonspecific viral-like illness associated with gastrointestinal or respiratory signs. Asian children are especially affected. Here we present a 3-yearold boy admitted to our hospital with fever and deterioration of consciousness. His nasopharyngeal swab for polymerase chain reaction revealed positive results for human parainfluenza 2 virus. The diagnosis of acute necrotizing encephalopathy was made by cranial magnetic resonance imaging findings with symmetrical expansile hyperintense signals in bilateral thalami.