Acute Necrotizing Encephalopathy of Childhood: A Turkish Case

Unver O., Hasiloglu Z. I., Sahin S., Albayram M. S., Tastan Y., Uysal S.

CUKUROVA MEDICAL JOURNAL, cilt.39, sa.3, ss.641-645, 2014 (ESCI, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 3
  • Basım Tarihi: 2014
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.641-645
  • Anahtar Kelimeler: Acute necrotizing encephalopathy, children, parainfluenza virus
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Acute necrotizing encephalopathy of childhood is a rare form of acute encephalopathy of unknown etiology characterized by typical symmetrical lesions in the thalami, with variable involvement of the white matter, brainstem and cerebellum. Clinically there is a rapid neurologic deterioration after a short period of a nonspecific viral-like illness associated with gastrointestinal or respiratory signs. Asian children are especially affected. Here we present a 3-yearold boy admitted to our hospital with fever and deterioration of consciousness. His nasopharyngeal swab for polymerase chain reaction revealed positive results for human parainfluenza 2 virus. The diagnosis of acute necrotizing encephalopathy was made by cranial magnetic resonance imaging findings with symmetrical expansile hyperintense signals in bilateral thalami.