Genotypes of hepatitis a virus in Turkey: first report and clinical profile of children infected with sub-genotypes IA and IIIA.

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Yilmaz H., Karakullukcu A., Turan N., Cizmecigil U. Y., Yilmaz A., Ozkul A. A., ...Daha Fazla

BMC infectious diseases, cilt.17, sa.1, ss.561, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1186/s12879-017-2667-3
  • Dergi Adı: BMC infectious diseases
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.561
  • Anahtar Kelimeler: Hepatitis a virus sequencing, Phylogenetic, VP1/VP2A, VP1/VP3, Turkey, ENTERIC VIRUSES, OUTBREAKS, REGION, CIRCULATION, VACCINATION, SHELLFISH, STRAINS
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Background: Hepatitis A virus (HAV) is a food and water-borne virus causing clinical (mainly hepatitis) and subclinical disease in humans. It is important to characterize circulating strains of HAV in order to prevent HAV infections using efficacious vaccines. The aim of this study was the detection and characterization of the circulating strains of HAV in Turkey by performing serology, RT-PCR, sequencing and phylogenetic analysis.