Retroperitoneal fibrosis caused by pergolide in a patient with Parkinson's disease
NETHERLANDS JOURNAL OF MEDICINE, cilt.62, sa.10, ss.389-392, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 62 Sayı: 10
- Basım Tarihi: 2004
- Dergi Adı: NETHERLANDS JOURNAL OF MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.389-392
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Retroperitoneal fibrosis (RPF) is an uncommon disorder that may cause ureteric obstruction with renal damage. Pergolide, a dopaminergic agonist used in the treatment of Parkinson's disease, has rarely been related to the development of RPF. We report on a 78-year-old woman with Parkinson's disease who presented with hydroureteronephrosis and developed RPF and serosal fibrosis during treatment with pergolide. Following discontinuation of pergolide therapy and placement of a double-J stent, her renal function improved. Inflammatory markers returned to normal limits within two months and the retroperitoneal fibrotic mass became smaller.