Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension
ARCHIVES OF MEDICAL RESEARCH, cilt.37, sa.5, ss.602-606, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 5
- Basım Tarihi: 2006
- Doi Numarası: 10.1016/j.arcmed.2005.12.002
- Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.602-606
- Anahtar Kelimeler: leptin, obesity, atherosclerosis, oxidative stress, nitric oxide, OXIDATIVE STRESS, ACTIVATION, EXPRESSION, INSULIN
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
Background. Recent evidence suggested that leptin-induced oxidative stress in human endothelial cells in vivo and increased oxidative stress in human essential hypertension may further contribute to both the development of atherosclerosis and other cardiovascular diseases. We investigated the association of plasma leptin levels with plasma lipid peroxidation and nitric oxide metabolites (NOx) in obese hypertensive atherosclerosis model.