THE FAT PAT TISSUE EXPRESSES A PATHOGENIC PROFILE OF INFLAMMATORY MEDIATORIES AND 4-HNE IN PATIENTS WITH OSTEOARTHRITIS
ACTA MEDICA MEDITERRANEA, cilt.37, sa.2, ss.1045-1051, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.19193/0393-6384_2021_2_160
- Dergi Adı: ACTA MEDICA MEDITERRANEA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.1045-1051
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Introduction: In this study we aimed to estimate if there is a releation between some inflammatory or adipocyte-derived cytokines as IL-1 beta, IL-6, TNF-alfa, VEGF, 4-HNE, macrophages, mast cells and osteoarthirites. Especially 4-HNE which associated obesity is a new marker for estimating the chondral injuries and there is a poor evidence of it's effect on IFP and osteoarthritis.