Low Dose UVA-1 Treatment in Atopic Dermatitis: Does Treatment Response Depend on Age and Gender?


Özkoca D., Uzunçakmak T. K., Caf N., Kutlubay Z.

Journal Of The Turkish Academy Of Dermatology, cilt.17, sa.1, ss.18-21, 2023 (Hakemli Dergi)

Özet

Background: UVA-1 is one of the anti-inflammatory treatment alternatives for atopic dermatitis.

Materials and Methods: The aim of this study is to evaluate the efficacy of low dose UVA-1treatment in atopic dermatitis. The patient files

of the 19 atopic dermatitis patients who received low dose UVA-1 (10-15 J/cm2

, 5 days a week) treatment were analysed retrospectively.

Results: The complete remission rate was 84%. The mean of the cumulative dose was 236.05 J and the mean of treatment sessions was 16.1.

Mann-Whitney U test showed that there is no relationship between age and treatment response (p=1.00). Fischer’s extract test showed that

there is no relationship between gender and treatment response (p=0.582).

Conclusion: It was concluded that low dose UVA-1 is an efficacous treatment for atopic dermatitis regardless of the patient’s age and gender.

A lower cumulative dose with a greater number of treatment sessions is required for low dose UVA-1 compared to high dose UVA-1 in the

treatment of atopic dermatitis.

Keywords: Atopic dermatitis, Low dose, Phototherapy, UVA-1