Anti-inflammatory and ultrastructural effects of Turkish propolis in a rat model of endotoxin-induced uveitis
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA, cilt.54, sa.1, ss.49-57, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 54 Sayı: 1
- Basım Tarihi: 2016
- Doi Numarası: 10.5603/fhc.a2016.0004
- Dergi Adı: FOLIA HISTOCHEMICA ET CYTOBIOLOGICA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.49-57
- Anahtar Kelimeler: acute uveitis, propolis, lipopolysaccharide, HIF-1 alpha, TNF-alpha, IHC, electron microscopy, rat, NF-KAPPA-B, PYRROLIDINE DITHIOCARBAMATE, IN-VITRO, INFLAMMATION, HYPOXIA, EXPRESSION, INHIBITOR, DISEASES, VIVO
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
Introduction. Experimental animal models of acute uveitis, an inflammatory eye disease, can be established via endotoxin-induced inflammation. Propolis, a natural substance collected by honeybees from buds and tree exudates, has antioxidant, antibacterial, antiviral, and anti-inflammatory effects. We investigated the effects of propolis, obtained from the Sakarya province of Turkey, on endotoxin-induced uveitis using immunohistochemical, ultrastructural, and biochemical approaches.