Long-term follow- up of patients who developed contrast-induced acute kidney injury in patients with acute coronary syndrome

Uluslararası Katılımlı 31. Türk Kardiyoloji Kongresi, Antalya, Türkiye, 22 - 25 Ekim 2015, ss.9, (Özet Bildiri)

Introduction: Patients with acute coronary syndrome (ACS) have a 3-fold higher risk of developing contrastinduced

acute kidney injury (CI-AKI). The association of contrast-induced acute kidney injury (CI-AKI) on

long-term prognosis in ACS patients has not been fully reported. The aim of our study was to evaluate the

predictors of CI-AKI and long-term prognosis who developed CI-AKI in patients with ACS.

Materials and Method: 1200 ACS patients underwent coronary angiography and/or percutaneous coronary

interventions (PCI) were analyzed. Patients with high risk ACS (requiring urgent coronary angiography and

cardiogenic shock) and those who had advanced left ventricle dysfunction, acute renal failure or end-stage

renal failure requiring dialysis were excluded. A total of 1083 ACS patients were enrolled. CI-AKI was defined

as an increase of at least 0.5 mg/dL and/or an increase of at least 25% of serum creatinine levels within

48-72 hours after the procedure. Primary endpoint was defined as all-cause mortality, MI and cerebrovascular

event (CVE) at 1-year follow-up.

Results: Results are displayed in table 1 and table 2.

Discussion and Conclusion: Our study demonstrated that risk of CI-AKI development was more frequently

seen in patients with ACS. Also, patients who developed CI-AKI had worse prognosis at long- term follow-up.