Akademik Veri Yönetim Sistemi
Neuroradiology, 2026 (SCI-Expanded, Scopus)
Purpose: This study aimed to evaluate the complications encountered during and following the treatment of patients with flow-diverter stents, as well as the secondary interventions employed to manage these complications. Methods: We retrospectively analyzed the preprocedural, periprocedural, and postprocedural data of 660 patients with intracranial aneurysms who were treated via flow diversion between March 2008 and October 2023. Complications related to flow diversion were systematically assessed. Results: The median follow-up period was 81 months (range: 12–180 months). A total of 64 patients (9.70%) experienced at least one complication, corresponding to 65 complication events. Early complications occurred in 33 patients (5.0%), whereas late complications were observed in 31 patients (4.70%). The overall technical complication rate was 3.03%, and the clinical complication rate was 6.82%. Secondary interventions were required in 39 patients (5.91%). Procedure-related mortality and morbidity rates were 0.76% and 4.55%, respectively. Technical complications include stent shortening/migration, stent deformation, stent fracture, stent layer separation, and distal wire dissection. Clinical complications include intimal hyperplasia causing significant stenosis, stent occlusion, carotid-cavernous fistula, thromboembolic events, hemorrhagic events, and rare events such as non-ischemic cerebral enhancing (NICE) lesions and diffuse alveolar hemorrhage. Conclusion: Flow diversion represents an effective reconstructive strategy for intracranial aneurysms, demonstrating durable long-term occlusion in a large single-center cohort. Although complication patterns evolved over time, the retrospective design and concurrent changes in devices and treatment protocols preclude definitive causal inferences. This experience may serve as a practical reference for complication recognition and bailout management.