Treatment of iodine-negative thyroglobulin-positive thyroid cancer: differences in outcome in patients with macrometastases and patients with micrometastases

Kabasakal, LEVENT; Selcuk, NA; Shafipour, H; Ozmen, O; Onsel, Çetin; Uslu, I

doi:10.1007/s00259-004-1516-y

Treatment of iodine-negative thyroglobulin-positive thyroid cancer: differences in outcome in patients with macrometastases and patients with micrometastases

Kabasakal L., Selcuk N., Shafipour H., Ozmen O., Onsel C., Uslu I.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, cilt.31, sa.11, ss.1500-1504, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 31 Sayı: 11
Basım Tarihi: 2004
Doi Numarası: 10.1007/s00259-004-1516-y
Dergi Adı: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1500-1504
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Purpose. During the follow-up of patients with well-differentiated thyroid carcinoma, some patients have elevated serum thyroglobulin (Tg) levels without any evidence of radioiodine accumulation on diagnostic whole-body scan (d-WBS). The treatment strategy in these patients is considered a clinical dilemma, with some groups recommending blind use of high-dose radioiodine therapy. The aim of this study was to evaluate whether or not high doses of radioiodine have beneficial effects in these patients.