Protective role of intratympanic nigella sativa oil against gentamicin induced hearing loss

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Edizer D. T., Yigit O., Cinar Z., GÜL M., Kara E., Yigitcan B., ...Daha Fazla

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, cilt.97, ss.83-88, 2017 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 97
• Basım Tarihi: 2017
• Doi Numarası: 10.1016/j.ijporl.2017.03.034
• Dergi Adı: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.83-88
• Anahtar Kelimeler: Nigella sativa, Gentamicin, Hearing loss, Intratympanic, AMINOGLYCOSIDE-INDUCED OTOTOXICITY, CISPLATIN-INDUCED NEPHROTOXICITY, INDUCED HAIR CELL, GUINEA-PIGS, ANIMAL-MODEL, RATS, PREVENTION, THYMOQUINONE, INHIBITOR, TOXICITY
• İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Objective: Aminoglycosides, used to combat with life-threatening infections, have a substantial risk of hearing loss. Nigella sativa is an annual herbaceous plant and used for treatment of many diseases for ages. We aimed to investigate the protective role of intratympanic nigella sativa oil against gentamicin induced hearing loss in an animal model.