Hoffmann's syndrome and pituitary hyperplasia in an adolescent secondary to Hashimoto thyroiditis

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Cebeci A. N., Guven A., Saltik S., Mesci C.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.26, ss.747-751, 2013 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 26
• Basım Tarihi: 2013
• Doi Numarası: 10.1515/jpem-2012-0249
• Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.747-751
• İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Background: Diffuse muscle hypertrophy is a rare complication of acquired hypothyroidism. When accompanied by stiffness, weakness, and painful muscle cramps, the condition is known as Hoffmann's syndrome (HS). HS is usually seen in young adults due to long-standing untreated primary hypothyroidism. We report a very rare case of HS with muscle hypertrophy and pituitary hyperplasia complicating hypothyroidism in an adolescent.