The Frequency and Clinical Findings of Human Bocavirus in Hospitalized Children: ATertiary Hospital Experience in İstanbul
JOURNAL OF PEDIATRIC INFECTION, cilt.20, sa.1, ss.19-27, 2026 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.5578/ced.20260117
- Dergi Adı: JOURNAL OF PEDIATRIC INFECTION
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Central & Eastern European Academic Source (CEEAS), CINAHL, EMBASE, TR DİZİN (ULAKBİM), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.19-27
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Objective: Human bocavirus (HBoV), the predominant viral contributor to respiratory tract infections (RTIs) in children, remains a global health challenge. This study aimed to delineate the frequency and clinical manifestations of HBoV in pediatric patients admitted to a tertiary healthcare hospital's pediatric infectious diseases clinic in & Idot;stanbul, thereby contributing to a broader understanding of its impact. Material and Methods: A retrospective review of children under 18 years of age hospitalized for RTIs was conducted from June 2021 to February 2023. The demographic, clinical, and laboratory data were evaluated using descriptive statistics and comparative tests. Results: A total of 48 hospitalized children tested positive for HBoV. Median age was 18.5 months [interquartile range (QR):9.0-30.0], and 58.3% of the patients were male. Most patients (85.4%) had no chronic diseases and 66.7% were born via cesarean section. Autumn was the most frequent admission season (64.6%). The predominant symptoms were coughing (77.1%) and fever (75.0%). Respiratory distress was observed in 47.9% of the patients, and 75.0% required oxygen supplementation, primarily via masks (41.7%). Chest radiographs showed infiltration in 41.7% of the cases. Inhaler use was reported in 62.5% of patients, whereas antibiotics were initiated in 85.4% the of patients.Oseltamivir was administered only to patients with co-infection (20.0%, p= 0.043), and steroid use was more frequent in this group (46.7% vs. 22.2%, p= 0.090). Among all patients, 22.9% required intensive care unit admission. Co-infection with at least one other respiratory virus, most commonly respiratory syncytial virus (20.8%), was observed in 62.5% of the cases. No significant differences were found between the HBoV-only and HBoV-co-infected groups in terms of demographic variables, symptoms, laboratory parameters, or hospitalization duration. Conclusion: This study elucidated the pivotal role of HBoV in pediatric RTIs. HBoV is associated with a high rate of coinfection with other respiratory viruses. This study contributes to a broader understanding of HBoV infections and can guide clinicians in implementing appropriate treatment strategies.