Comparative biochemical and histopathological evaluations proved that receptacle is the most effective part of Cynara scolymus against liver and kidney damages

Sumer E., Senturk G., Demirel O. U., YEŞİLADA E.

JOURNAL OF ETHNOPHARMACOLOGY, cilt.249, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 249
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jep.2019.112458
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, International Bibliography of Social Sciences, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, CINAHL, EMBASE, Index Islamicus, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Acute hepatotoxicity, Nephrotoxicity, Artichoke extracts, Histopathology, ARTICHOKE LEAF EXTRACT, PARACETAMOL-INDUCED HEPATOTOXICITY, INDUCED OXIDATIVE STRESS, ACETAMINOPHEN NEPHROTOXICITY, HEPATOPROTECTIVE ACTIVITY, PROTECTIVE PROPERTIES, ACTIVATED-CHARCOAL, RATS, TOXICITY, INJURY
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Ethnopharmacological relevance: The liver and kidney are among the most important organs in the body, where metabolic and elimination functions take place. During this process, liver and kidneys may suffer damage due to ingestion or formation of toxic metabolites leading to organ loss and even death. Artichoke (Cynara scolymus L.) leaf has long been recognized as a popular herbal remedy in traditional medicines with beneficial effects on liver.