Interleukin 17 alone is not a discriminant biomarker in early demyelinating spectrum disorders

Lebrun C., Cohen M., Pignolet B., Seitz-Polski B., Bucciarelli F., Benzaken S., ...Daha Fazla

JOURNAL OF THE NEUROLOGICAL SCIENCES, cilt.368, ss.334-336, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 368
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jns.2016.07.052
  • Dergi Adı: JOURNAL OF THE NEUROLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.334-336
  • Anahtar Kelimeler: Multiple sclerosis, Interleukin, Radiologically isolated syndrome, Clinically isolated syndrome, Biomarkers
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Background: Radiologically isolated syndrome (RIS) is a sub clinical demyelinating neurological disorder and to date no biomarker that triggers the seminal event has been identified. As for multiple sclerosis (MS), disease activity and clinical course are unpredictable. In MS, exploratory studies reported increased IL-17 levels in CSF but results in detecting IL-17 in serum at different stage of the disease are controversial.