Akademik Veri Yönetim Sistemi
31st International Epilepsy Congress, İstanbul, Türkiye, 5 - 09 Eylül 2015, cilt.56, ss.69, (Özet Bildiri)
Purpose: Surgery is a widely approved approach to long-standing epilepsy patients for whom the pharmacological option is both an economical burden for the patients and a futile way to compensate the
disease.
Method: Epilepsy surgery started in our department 20 years ago. We
performed a retrospective study on total 449 surgery patients starting
from 1995 to 2015. Patients’ operation dates, the age at operation, socioeconomic status, localization of the lesion, the pathologies and the operation type were collected and analyzed.
Results: Of the patientes analyzed 50% (225) were women and 50%
(224) were men. 15% (69) of patients were under the age of 12, 13%
(60) were between 13–18, 66% (297) were between 19–45 and 3%
(13) were over 45. There were 7 patients younger than 2 years.
According to years: 15% (67) were operated before 2000, 25%(111)
between 2000–2004, 30%(135) between 2005–2009, 28%(126)
between 2010–2014, unknown %2(10). 39.9%(179) of patients presented with mesial temporal sclerosis (MTS), 19.2%(86) with cortical
dysplasia (CD), 18.7%(84) with tumoral lesions, 6.7% (30) with dual
pathology, 1.1% (5) with developmental anomalies, 3.3%(15) with vascular lesions, 7.1%(32) others. %4(18) patients underwent corpus callosectomy, functional hemispherectomy and partial hemispherectomy.
Ten patients were lost to follow-up. Througout years the incidence of
mesial temporal sclerosis and cortical dysplasia have changed reciprocally. MTS before 1999-%18(32), 2000–2004:%41(73), 2005–2009:%
20(36), 2010–2014:%21(38). CD before 1999- %6(5), 2000–2004:%6
(5), 2005–2009:%44(38), 2010–2014:%44(38). Surgery techniques differed according to the time and type of the operation such as:14%(63)
amigdalohippocampectomy,34.3%(154) temporal lobectomy, 43%
(193) non-specific excision,0.7%(3) corpus callosectomy 4.2%(19)
Hemispherectomy, 0.4%(2) lobectomy(frontal and occipital). It is noteworthy to state that the trend in amigdalohippocampectomy declined
and replaced with anterior temporal lobectomy.
Conclusion: Epilepsy surgery is an effective treatment in well selected
cases. The pathology and surgical procedures are changing during the
years. Moreover number of children is increasing including the very
young ages.