VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, cilt.17, sa.1, ss.32-35, 2011 (ESCI, TRDizin)
The most important goal of chronic hepatitis B treatment is hepatitis B surface antigen (HBsAg) seroclearance. The newly developed potent antiviral drugs are far from that goal even though they perfectly reduce the viral load. Increased HBsAg loss and life expectancy were observed in patients with response to interferon-based therapy. In this study, we aimed to evaluate the rate of HBsAg loss and to detect the triggering factors in chronic hepatitis B patients who were followed-up at least 4 years (4-18 years).