Microbial Biosynthesis of Vitamins


Kocazeybek B. S., Sarıbaş A. S., Demirci M., Kırmusaoğlu S.

A Guide to Vitamins and Their Effects on Disease, Ata Alturfan,Ebru Alturfan, Editör, Cambridge Scholars Publishing Ltd, Newcastle Upon Tyne, ss.6-15, 2023

  • Yayın Türü: Kitapta Bölüm / Ders Kitabı
  • Basım Tarihi: 2023
  • Yayınevi: Cambridge Scholars Publishing Ltd
  • Basıldığı Şehir: Newcastle Upon Tyne
  • Sayfa Sayıları: ss.6-15
  • Editörler: Ata Alturfan,Ebru Alturfan, Editör
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Vitamins are organic molecules that function as coenzyme precursors. Theirpresence is vital to regulate the biochemical processes in living cells needed for survival. However, humans can’t synthesize all the necessary vitamins
required to have a healthy metabolism. Hence, these vitamins should be obtained from exogenous sources such as the products of human gut microbiota and foods (1). The enormous surface of the human gastrointestinal tract (250–400 m2) is exposed to nearly 60 tonnes of food passing through including the microorganisms from the environment (2, 3). Bacteria, archaea, and eukarya are gut microbiota colonizing the gastrointestinal tract and there is obviously a mutually beneficial relationship between the members of the gut microbiota and the host (4). The estimated number of gut microbiota is 1014, which is 10 times higher than the number of human cells in the body (5, 6). The gut microbiota has many benefits for the human gastrointestinal tract, such as strengthening the gut integrity (7), supply of energy (8), protection against environmental pathogens (9), and regulating the host immunity (10). However, alteration in the microbial composition
of the gut microbiota is known as dysbiosis, and it may disrupt all of these
beneficial effects.


Vitamins are organic molecules that function as coenzyme precursors. Theirpresence is vital to regulate the biochemical processes in living cells needed for survival. However, humans can’t synthesize all the necessary vitamins
required to have a healthy metabolism. Hence, these vitamins should be obtained from exogenous sources such as the products of human gut microbiota and foods (1). The enormous surface of the human gastrointestinal tract (250–400 m2) is exposed to nearly 60 tonnes of food passing through including the microorganisms from the environment (2, 3). Bacteria, archaea, and eukarya are gut microbiota colonizing the gastrointestinal tract and there is obviously a mutually beneficial relationship between the members of the gut microbiota and the host (4). The estimated number of gut microbiota is 1014, which is 10 times higher than the number of human cells in the body (5, 6). The gut microbiota has many benefits for the human gastrointestinal tract, such as strengthening the gut integrity (7), supply of energy (8), protection against environmental pathogens (9), and regulating the host immunity (10). However, alteration in the microbial composition
of the gut microbiota is known as dysbiosis, and it may disrupt all of these
beneficial effects.