The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin

Seven, Pinar; Seven, Ismail; KARAKUŞ, SELCAN; Mutlu, Seda; Kaya, Seyma; Arkali, Gozde; İLGAR, MERVE; Tan, EZGİ; Sahin, Yesim; Ismik, DENİZ; Kilislioglu, Ayben

doi:10.1016/j.joim.2021.08.002

The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin

Seven P. T., Seven I., KARAKUŞ S., Mutlu S. I., Kaya S. O., Arkali G., ...Daha Fazla

JOURNAL OF INTEGRATIVE MEDICINE-JIM, cilt.19, sa.5, ss.451-459, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19 Sayı: 5
Basım Tarihi: 2021
Doi Numarası: 10.1016/j.joim.2021.08.002
Dergi Adı: JOURNAL OF INTEGRATIVE MEDICINE-JIM
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
Sayfa Sayıları: ss.451-459
Anahtar Kelimeler: Cisplatin, Nano-propolis, Reproductive system, Testicular damage, REPRODUCTIVE TOXICITY, PROTECTIVE ROLE, ANTIOXIDANT CAPACITY, OXIDATIVE DAMAGE, SPERM QUALITY, CYCLOSPORINE, EXTRACT, SPERMATOGENESIS, NANOPARTICLES, CHLORPYRIFOS
İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objective: Chemotherapeutic drugs, such as cisplatin (CP), which are associated with oxidative stress and apoptosis, may adversely affect the reproductive system. This study tests whether administration of propolis and nano-propolis (NP) can alleviate oxidative stress and apoptosis in rats with testicular damage induced by CP.