Antiglycation Activities of Some Plant Extracts

Yanardağ R., Başoğlu Çetin B.

II. International Eurisan Agriculture and Natural Sciences Congress, Baku, Azerbaycan, 11 - 15 Eylül 2018, ss.128, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Baku
  • Basıldığı Ülke: Azerbaycan
  • Sayfa Sayıları: ss.128
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Antiglycation Activities of Some Plant Extracts 

Bihter Basoglu Cetin,  Refiye Yanardag

Istanbul University, Faculty of Engineering, Department of Chemistry, 34320 Avcilar-Istanbul /Turkey                                                                                                                                                                                                                                                                                                                                                                

 

 

Advanced glycation end products (AGEs) are a complex and heterogeneous groups of compounds  that have been implicated in diabetes related complications. Their concentration increases with age. The AGEs are closely associated with hyperglycemia. Several synthetic and natural products have been tested as inhibitors as AGEs formation and AGEs breakers as potential therapeutics for management of diabatic complications. This pharmaceutical shows some adverse effects. For this reason, there is a need for the development of new efficacious drugs, with minimal or no side effects. In our study we have examined antiglycation activities of aqueous extracts prepared from different 17 plants such as laurel leaf, mulberry leaf, melissa officinalis leaf, mallow leaf, pistacia atlantica Desf.  All the plant extracts exhibited antiglycation activites. The antiglycation activities of these plant extracts were found to increase dose depently. Pistacia atlantica Desf extract was found as the most effective extract among the plant extracts.These data indicate that these plant extracts could be used to prevent glycation associated complicatons in diabetes.