Can Amantadine Ameliorate Neurocognitive Functions After Subarachnoid Haemorrhage? A Preliminary Study

Creative Commons License

Akcil E. F., Dilmen O. K., Vehid H., Tunali Y.

TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION, cilt.46, sa.2, ss.100-107, 2018 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/tjar.2018.20280
  • Dergi Adı: TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.100-107
  • Anahtar Kelimeler: Amantadine, subarachnoid haemorrhage, neurocognitive functions, TRAUMATIC BRAIN-INJURY, NMDA RECEPTOR ANTAGONIST, MEMANTINE, MICRODIALYSIS, DEFICITS, TRIAL, SCALE, STATE, COMA
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objective: Aneurysmal subarachnoid haemorrhage (SAH) may have devastating effects on patients. Motor and neurocognitive impairments may arise depending on the location and grade of the SAH. Although the effects of amantadine on neurocognitive function after traumatic brain injury have been widely studied to the best of our knowledge, their effects on recovery from SAH in humans have not been studied. The present study aimed to evaluate how amantadine influences improvement in neurocognitive function in patients with aneurysmal SAH over a period of six months.