The seizures that wake up with the patient: The effect of sleep deprivation and short sleep on epilepsy with eyelid myoclonia

GÜLEÇ, BADE; Yasguclukal, MİRAY; Elmali, Ayse; Yalcinkaa, Cengiz; DEMİRBİLEK, AHMET

doi:10.1016/j.neucli.2023.102846

The seizures that wake up with the patient: The effect of sleep deprivation and short sleep on epilepsy with eyelid myoclonia

GÜLEÇ B., Yasguclukal M., Elmali A. D., Yalcinkaa C., DEMİRBİLEK A. V.

NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY, cilt.53, sa.1, 2023 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 53 Sayı: 1
Basım Tarihi: 2023
Doi Numarası: 10.1016/j.neucli.2023.102846
Dergi Adı: NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, EMBASE, MEDLINE
Anahtar Kelimeler: EEG, Eyelid myoclonia, Photoparoxysmal, response, JEAVONS SYNDROME, ILAE COMMISSION, CLASSIFICATION, ABSENCES, ADULTS, EEG
İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Objective: In this study, our aim was to demonstrate the effect of sleep deprivation, short sleep, and awakening on photoparoxysmal responses (PPR) and eyelid myoclonia (EM) in patients with Epilepsy with Eyelid Myoclonia (E-EM).Methods: E-EM patients with at least 1 year of follow-up in our clinic were included in the study. Video EEG(v-EEG) analyses were divided into three periods of wakefulness, sleep, and awaken-ing. The PPR and onset of EMs were investigated.Results: 32 patients met the study criteria, of which 56.3% (n = 18) were male. The mean age at disease onset was 7.7 +/- 4.1 years. The mean age at EEG recording was 12.4 +/- 4.0 years. EM was observed only on awakening in 78.1% of patients (n = 22), of which it was seen only during inter-mittent photic stimulation (IPS) in 43.7% (n = 14). Eye closure (EC) sensitivity was detected in all patients. The proportion of patients with a PPR was significantly higher on awakening than before sleep (p = 0.01).Conclusions: This study showed that EM is most prominent and sometimes can only be detected in the awakening period in E-EM. In order to detect E-EM, v-EEG recordings including both pre -sleep and post-sleep wakefulness periods should be recorded, with intermittent photic stimula-tion performed in both periods.(c) 2023 Elsevier Masson SAS. All rights reserved.