Akademik Veri Yönetim Sistemi
Bağcılar Tıp Bülteni, cilt.9, ss.21-30, 2024 (Hakemli Dergi)
Objective: While there are few studies on the use of ketamine for
sedation during magnetic resonance imaging (MRI) of pediatric patients,
we aimed to investigate the effects of low-dose ketamine administered
intramuscularly for vascular access on hemodynamics, sedation and
recovery, and MRI quality for the first time.
Method: A total of 193 pediatric patients aged 3 months to 15 years
who received sedation anesthesia for MRI were included in this study.
Ninety-nine subjects in the group (Group K) administered ketamine 2.5
mg/kg and below intramuscularly and the propofol-control group (Group
C), where 94 subjects were not administered intramuscular ketamine,
were divided into two groups. The groups were compared in terms of
demographic data, sedation and procedure times, anesthetic drug
doses, Ramsay sedation score, hemodynamic parameters, recovery time,
modified Aldrete recovery scores, MRI quality, and side effects.
Results: The mean values of first dose and additional dose propofol
mg/kg in Group K were 0.56 (0.45/0.71) - 0 (0/0), respectively, whereas
in Group C the values were 1.11 (0.87/1.33) - 0.14 (0/0.5), respectively. In
Group K, the mean systolic arterial pressures, diastolic arterial pressures,
and median values of mean arterial pressures during the procedure
were found to be higher than those of Group C (p<0.001; =0.001; <0.001,
respectively). While the jaw-thrust maneuver was performed in two
patients in Group K, airway was required in one patient in Group C. The
relationship between the groups in terms of MRI quality was found to be
statistically significant (p<0.016).
Conclusion: It has been observed that low-dose intramuscular ketamine
(2.5 mg/kg and less) used in vascular access provides a positive efficacy
and safety profile with less sedative additional drugs, even in agitated
children during sedation anesthesia during pediatric MRI, and better MRI
quality is achieved.
Keywords: Intramuscular ketamine, magnetic resonance imaging,
pediatrics, propofol, sedation