EURASIAN JOURNAL OF PULMONOLOGY, cilt.10, sa.2, ss.147-152, 2008 (ESCI, TRDizin)
Dopamine agonists, particularly ergot preperations, are related to pulmonary or retroperitoneal fibrosis, or cardiac valvular diseases. Several hypotheses have been suggested to explain the pathophysiological mechanism, including toxic fibrogenesis, vascular theory, and immunological theory. The fibrotic disease is said to be often reversible if the drug is stopped quickly. Follow-up in patients treated with ergot-dopamin agonists is therefore important by monitoring the related symptoms, and regular screening tests.