Plasma total oxidant and antioxidant status after oral glucose tolerance and mixed meal tests in patients with polycystic ovary syndrome

KUCUKAYDIN, Zehra; DURAN, Cevdet; BASARAN, Mustafa; CAMLICA, Fatos; ERDEM, Sami; BASARAN, Ahmet; KUTLU, Orkide; BURNIK, Ferda; ELMAS, Halis; Gonen, MUSTAFA

doi:10.1007/s40618-016-0498-5

Plasma total oxidant and antioxidant status after oral glucose tolerance and mixed meal tests in patients with polycystic ovary syndrome

KUCUKAYDIN Z., DURAN C., BASARAN M., CAMLICA F., ERDEM S. S., BASARAN A., ...Daha Fazla

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, cilt.39, sa.10, ss.1139-1148, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 10
Basım Tarihi: 2016
Doi Numarası: 10.1007/s40618-016-0498-5
Dergi Adı: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1139-1148
İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Purpose Insulin resistance (IR) and increased oxidative stress (OS) are the characteristics of polycystic ovary syndrome (PCOS). In this study, we aimed to evaluate the effects of oral glucose tolerance (OGTT) and mixed meal tests (MMT) on plasma total oxidant (TOS) and total antioxidant status (TAS) in patients with PCOS and the relationship between these parameters and IR, calculated via homeostasis of model assessment-IR (HOMA-IR) and Matsuda's insulin sensitivity index (ISI) derived from OGTT and MMT.