Akademik Veri Yönetim Sistemi
5th Regional TIAFT Meeting, Diyarbakır, Türkiye, 9 - 11 Ekim 2024, ss.1, (Özet Bildiri)
Abstract
In both clinical and forensic situations the use of alternative matrices in toxicological analysis has grown significantly in importance recently. Additional information on drug exposure and analytical benefits can be obtained from samples that are not traditional biological samples like blood or urine. Toxicological analysis takes into account the pharmacokinetics of the substance by selecting the appropriate extraction method and analysis. Therefore, analytical chemistry, one of the most important branches of chemistry, plays a major role in practice.
Biological sample issues are of great concern in forensic toxicology, including chain of custody, preparation for analysis and selection of the appropriate analytical method. Recently, the seeking for alternative matrices in forensic toxicology (antemortem and postmortem) has been intensified and will probably continue. Its main advantage is its use in the absence of blood or urine. Obviously, there are pros and cons to each matrix and this may vary in the evaluation of the analysis of the findings.
The purpose of this paper to demonstrate the interpretation of the analysis results of our four latest studies regarding to alternative matrices including nail, hair, sweat and artificial CSF in forensic toxicology.
Keywords: Nail, hair, sweat, artificial CSF, analysis methods, results interpretation