Akademik Veri Yönetim Sistemi
5th Regional TIAFT Meeting, Diyarbakır, Türkiye, 9 - 11 Ekim 2024, ss.3, (Özet Bildiri)
Qualitative Analysis and Detection of the Pyrolytic Products of Salvia Smoking Substrates in the Synthetic cannabinoid Use
Fatma Bezirci, Zeynep Turkmen
1Istanbul University-Cerrahpaşa, The Institute of Forensic Sciences and Legal Medicine,
Department of Science, Istanbul, Türkiye
Introduction: Synthetic cannabinoids (SCs) are the most abused class of NPS. The common way of taking SCs is smoking after spraying the liquid on some dried local plants and smoking, or by inhaling the heated vapors. The acute toxicity of SC use is of particular concern in terms of forensic toxicology. Although numerous studies have been conducted on SCs, there is a lack of information on the identification of pyrolytic products and their toxicity during SC use and how this information can be used in the interpretation of forensic toxicology data.
Salvia is known as Sage from the Lamiaceae family. The word salvia is derived from the Latin word salveo (to save). Salvia L. is a plant that grows naturally in temperate regions of the world and has almost 1000 species. In Turkey, it includes 109 taxa, 97 species, 4 subspecies and 8 varieties, 51 of which are endemic. Salvia L. is an aromatic medicinal plant. It has been reported that it has been used in traditional folk medicine from the past to the present as a tea, ointment, tincture or extract and used as an analgesic, expectorant and carminative, antiperspirant, in the treatment of colds, bronchitis, tuberculosis, stomach disorders and menstrual disorders.
There are numerous compounds that change during the inhalation process. Several techniques are used in the literature to perform pyrolysis experiments, including cigarette smoking. Each technique is designed to collect specific types of compounds.
Aim: The aim of the study is to determine the compounds derived from the Salvia plant during pyrolysis and to distinguish them from those derived from SC use.
Method: In this study, the dried salvia sample, which had been crushed in a mortar, was then wrapped in cigarette paper. The pyrolysis products were collected by burning the paper like a cigarette, using a type of device designed to trap the smoke in the solution. This process was also repeated three times by burning the empty cigarette paper as control sample.
Results: In the pyrolysis of Salvia L. “styrene, 1,8-cineole, d-limonene, propanal, 2-beta-pinene and sabinene were detected by GC-MS.
Conclusions: These compounds are also applicable for analysis and toxicity assessment in post-mortem samples. Thus, this study, which includes a comprehensive characterization of the pyrolysis products associated with the herbal substrate, is also expected to be useful for the analysis and assessment of toxicity in post-mortem samples.
Keywords: Pyrolysis compounds, Herbal blends, Synthetic cannabinoids, Salvia, GC-MS