Synthesis, antielastase, antioxidant and radical scavenging activities of 4-(aza substituted) methylene substituted dihydroxy coumarines
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, cilt.28, sa.4, ss.870-875, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 4
- Basım Tarihi: 2013
- Doi Numarası: 10.3109/14756366.2012.692086
- Dergi Adı: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.870-875
- Anahtar Kelimeler: 4-alkylaminomethyl substituted dihydroxy coumarin derivatives, antioxidant activity, radical scavenging activity, antielastase activity, ANTIINFLAMMATORY ACTIVITY, BIOLOGICAL-ACTIVITY, ELASTASE ACTIVITY, DERIVATIVES, INHIBITORS, HIV, CAPACITY
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
A series of some 4-(aza substituted) methylene substituted dihydroxy coumarines were evaluated for their antioxidant and antielastase activities. Different in vitro methodologies such as total reducing power, 1,1-diphenyl-2-picrylhydrazil (DPPH.) free radical scavenging, ABTS radical scavenging activity were used as antioxidant activity. All the tested compounds exhibited potent free radical scavenging ability and antielastase activites.