Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children
TURKISH JOURNAL OF PEDIATRICS, cilt.41, sa.1, ss.67-71, 1999 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 1
- Basım Tarihi: 1999
- Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.67-71
- Anahtar Kelimeler: antinuclear antibodies, rheumatoid factor, Turkish children, JUVENILE CHRONIC ARTHRITIS, AUTOIMMUNE-DISEASE, HEP-2 CELLS, AUTOANTIBODIES, POPULATION, SUBSTRATE
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
The frequency of antinuclear antibodies (ANA) and rheumatoid factor (RF) was investigated in 118 apparently healthy children (56 male, 62 female). The mean age was 9.8+/-2.3 years. Antinuclear antibodies (ANA) were detected by indirect immunofluorescence, using a Hep-2 cell substrate. Nephelometry was used to quantify RF in 116 children. Five serum samples (4%, 3M, 2F) were ANA-positive in low titers and all had a speckled pattern. None of the ANA-positive children had other extractable antinuclear antibodies. Rheumatoid factor (RF) was over 25 IU/ml in tour children (3%, 3F, 1M), None of these was positive for both antibodies.