The Role of Focal Versus Generalized Epilepsy Classification and EEG Features on Antiepileptic Drug Choice

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Yeni S. N.

EPILEPSI, cilt.21, sa.2, ss.65-75, 2015 (ESCI, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5505/epilepsi.2015.46036
  • Dergi Adı: EPILEPSI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.65-75
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Objectives: The findings of focal interictal EEG are frequently emphasized in idiopathic generalized epilepsies. To avoid seizure aggravation, drugs such as carbamazepine (CBZ) should not be used in this group of patients. However, the reverse may also occur: In some epilepsy patients, there is a dramatic response to CBZ even with EEG activity revealing generalized spike and wave discharges. In this study, 8 patients with generalized spike and wave discharges presenting on interictal EEG and will be discussed on the basis of their treatment response to carbamazepine.