A systematic analysis of minipolymyoclonus in a cohort of patients with various neurological disorders
9th Congress of the European Academy of Neurology, Budapest, Macaristan, 1 - 04 Temmuz 2023, ss.169, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Basıldığı Şehir: Budapest
- Basıldığı Ülke: Macaristan
- Sayfa Sayıları: ss.169
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet
Özet
Background and aims: Minipolymyoclonus is specific type of myoclonus, which is defined as intermittent, arrhythmic involuntary movements that involve only fingers or, more rarely, the entire hand at the beginning of a posture or movement. In this study, we aimed to evaluate frequency, clinical and electrophysiological features of minipolymyoclonus. Methods: We retrospectively evaluated the medical records of cases who underwent polymyographic analysis in our laboratory between 2010 and 2022. Among them, we identified clinical and electrophysiological features of patients with irregular, jerky, involuntary movements in the fingers or hands and myoclonic discharges at different amplitudes in the distal hand muscles on clinical examination and polymyography. Results: Minipolymyoclonus was detected in 25 patients among 163 patients (mean age: 56±20.2 years; age range 17 and 84 years; 6 women). There were patients with multisystem atrophy (n=6), Parkinson’s disease (n=3), other movement disorders (n=3), amyotrophic lateral sclerosis (n=1), hereditary polyneuropathy (n=5), chronic inflammatory polyneuropathy (n=4) and acute inflammatory polyneuropathy (n=3). EMG bursts were in sequential patterns. EMG burst durations were between 50-100 ms. and often discharged simultaneously in several muscles of the same limb. C reflex was detected in three patients. Giant SEP was not detected. Conclusion: Our findings suggest that minipolymyoclonus is a non-specific phenomenon that can accompany many neurological manifestations. Detection of the C reflex in only 3 patients suggests that the cortical component is rarer. Disclosure: Nothing to disclose.