Preparation, characterization and antibacterial effect of 2-methoxy-6-(5-H/Me/Cl/NO2-1H-benzimidazol-2-yl)phenols and some transition metal complexes

Tavman A., Ikiz S., Bagcigil A. F., Ozgur N. Y., Ak S.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, cilt.74, sa.5, ss.537-548, 2009 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74 Sayı: 5
  • Basım Tarihi: 2009
  • Doi Numarası: 10.2298/jsc0905537t
  • Dergi Adı: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.537-548
  • Anahtar Kelimeler: benzimidazolylphenols, complexes, antibacterial activity, ANTIMICROBIAL ACTIVITY, STRUCTURAL-CHARACTERIZATION, IRON(III) COMPLEXES, ZINC(II), LIGANDS, NICKEL(II), COBALT(II), ION
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

2-Methoxy-6-(5-H/methyl/chloro/nitro-1H-benzimidazol-2-yl)phenols (HLx; x = 1-4, respectively) ligands and HL1 complexes with Fe(NO3)(3), Cu(NO3)(2), AgNO3 and Zn(NO3)(2) were synthesized and characterized. The structures of the compounds were confirmed based on elemental analysis, molar conductivity, magnetic moment, FT-IR, H-1- and C-13-NMR. The antibacterial activity and minimum inhibitory concentration (MIC) of the free ligands, their hydrochloride salts and the complexes were evaluated using the disk diffusion method in dimethyl sulfoxide (DMSO) and the dilution method, respectively, against 9 bacteria. HL1 and HL3, as well as the Cu(II) and Zn(II) complexes, showed antibacterial activity against Gram-positive bacteria.