Stereochemical assignments of aldol products of 2-arylimino-3-aryl-thiazolidine-4-ones by 1H NMR
MAGNETIC RESONANCE IN CHEMISTRY, cilt.50, sa.5, ss.402-405, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 5
- Basım Tarihi: 2012
- Doi Numarası: 10.1002/mrc.3813
- Dergi Adı: MAGNETIC RESONANCE IN CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.402-405
- Anahtar Kelimeler: NMR, 1H, 3JH, H coupling constants, stereochemical assignments, aldol reaction, axial chirality, intramolecular hydrogen bonding, DERIVATIVES, POTENT
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
The aldol reactions of 2-arylimino-3-aryl-thiazolidine-4-ones with benzaldehyde carried out at -78 degrees C were found to produce sec-carbinols. Intramolecular hydrogen bonding within the aldol products forming a six-membered ring enabled the assignment of stereochemistries of the major and minor diastereomers via analysis of the syn and anti 3JH,H 1H NMR coupling constants. Copyright (c) 2012 John Wiley & Sons, Ltd.