Effects of Ganoderma lucidum on Obstructive Jaundice-induced Oxidative Stress
ASIAN JOURNAL OF SURGERY, cilt.33, sa.4, ss.173-180, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 4
- Basım Tarihi: 2010
- Doi Numarası: 10.1016/s1015-9584(11)60003-1
- Dergi Adı: ASIAN JOURNAL OF SURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.173-180
- Anahtar Kelimeler: direct hyperbilirubinaemia, DNA damage, experimental cholestasis, Ganoderma lucidum, obstructive jaundice, oxidative stress, LIVER-INJURY, DAMAGE, RATS, POLYSACCHARIDE, CIRRHOSIS, HYPOXIA, MODEL
- İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır
Özet
OBJECTIVE: Obstructive jaundice develops after occlusion of the common bile duct. Direct hyperbilirubinaemia, which occurs secondary to the condition, causes various life-threatening pathologies. Cytoprotective effects of Ganoderma lucidum (GL) have previously been shown. In this study, the effects of GL on oxidative stress and oxidant DNA damage in experimental obstructive jaundice were evaluated.