Impact of Nail Psoriasis on Quality of Life: A Turkish Validation Study of NPQ-10 and NAPPA


Altan Ferhatoglu Z., Zengin M., Yildirim G., ENGİN B., SERDAROĞLU Ü. S., Goktay F.

Skin Appendage Disorders, ss.1-7, 2026 (ESCI, Scopus) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1159/000550467
  • Dergi Adı: Skin Appendage Disorders
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE
  • Sayfa Sayıları: ss.1-7
  • Anahtar Kelimeler: Nail psoriasis, NAPPA, NPQ-10, Quality of life
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Evet

Özet

Introduction: Nail psoriasis significantly impairs quality of life (QoL). General dermatology instruments often lack sensitivity for specific nail-related burdens. This study aimed to validate the Turkish versions of the Nail Psoriasis Quality of Life Scale (NPQ-10) and the Nail Assessment in Psoriasis and Psoriatic Arthritis (NAPPA). Methods: This cross-sectional validation study included 71 patients (42 male, 29 female). The questionnaires were translated into Turkish following international guidelines. Reliability and validity were assessed by analyzing correlations with the Dermatology Life Quality Index (DLQI) and clinical parameters (PASI, NAPSI). Results: The sample showed a male predominance (59.2%). DLQI scores showed a moderate positive correlation with NPQ-10 (r = 0.453) and NAPPA-QoL (r = 0.477). Patients with toenail involvement had significantly higher QoL impairment. While men had higher clinical severity scores (PASI), women reported higher stigma-related scores. Conclusion: The Turkish versions of NPQ-10 and NAPPA are valid and reliable instruments. They capture specific physical and psychosocial burdens of nail psoriasis more accurately than general tools, particularly regarding toenail involvement and stigma. Incorporating these tools into practice is recommended.