Epilepsy and Pregnancy: Retrospective Analysis of 58 Cases


GÖK K., YILMAZ E., ÖZGÜL A., BOSTANCI M. S., ÖZDEN S., GÖK N. R.

Haydarpaşa Numune Medical Journal, cilt.62, sa.2, ss.178-182, 2022 (TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.14744/hnhj.2022.37431
  • Dergi Adı: Haydarpaşa Numune Medical Journal
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.178-182
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

Introduction: This study aimed to retrospectively evaluate the perinatal outcomes of pregnant women diagnosed with epilepsy followed in our clinic. Methods: In this retrospective cohort study, a total of 58 pregnant women diagnosed with epilepsy who were delivered after pregnancy follow-up at Sakarya University Training and Research Hospital Gynecology and Obstetrics Clinic between January 2015 and March 2021 were evaluated. Results: The mean age of the patients was 28.4±5.7 years. It was determined that 25 cases (43.1%) had seizures during pregnancy. It was determined that the rate of seizures during pregnancy in those who had a seizure in the past 1 year before pregnancy was statistically significantly higher than those who had their last seizure longer than 1 year (p=0.000). It was found that 72.7% of the patients in the polytherapy group had epileptic seizures during pregnancy, and this rate was significantly higher than the monotherapy group (p=0.042). Discussion and Conclusion: The frequency of seizures during pregnancy is strongly associated with epileptic seizure status in the last year before pregnancy and multiple antiepileptic therapies.