Biocompatibility of 17-4 PH stainless steel foam for implant applications

Mutlu I., Oktay E.

BIO-MEDICAL MATERIALS AND ENGINEERING, cilt.21, sa.4, ss.223-233, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3233/bme-2011-0671
  • Dergi Adı: BIO-MEDICAL MATERIALS AND ENGINEERING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.223-233
  • Anahtar Kelimeler: Metal foam, implant, 17-4 PH stainless steel, biocompatibility, cytotoxicity, IN-VITRO, TITANIUM, CYTOTOXICITY
  • İstanbul Üniversitesi-Cerrahpaşa Adresli: Hayır

Özet

In this study, biocompatibility of 17-4 PH stainless steel foam for biomedical implant applications was investigated. 17-4 PH stainless steel foams having porosities in the range of 40-82% with an average pore size of around 600 mu m were produced by space holder-sintering technique. Sintered foams were precipitation hardened for times of 1-6 h at temperatures between 450-570 degrees C. Compressive yield strength and Young's modulus of aged stainless steel foams were observed to vary between 80-130 MPa and 0.73-1.54 GPa, respectively. Pore morphology, pore size and the mechanical properties of the 17-4 PH stainless steel foams were close to cancellous bone. In vitro evaluations of cytotoxicity of the foams were investigated by XTT and MTT assays and showed sufficient biocompatibility. Surface roughness parameters of the stainless steel foams were also determined to characterize the foams.